While Thirteen helps House with the transfusion, House tells her that he did some snooping and learned that her mother passed away at a young age. He asks if she had Parkinson's. Thirteen says that it was Huntington's Disease. Because of her hand trembling, Thirteen tells House that she will leave when the case is over. House tells her not to because her trembling was caused by his switching her decaf coffee for regular. Although she has a 50% chance of getting Huntington's, Thirteen has not been tested for it. She says not knowing has inspired her to do things that she would normally have been afraid to do, like working for House. She echoes Flynn's sentiment that unless worrying is some kind of treatment, she doesn't want to know.
House does get sick from the transfusion, and passes out. The team uses House as the test donor, and tests his organs to discover what is wrong with Flynn. When House comes to, he accuses Thirteen of dosing him with narcotics to make him pass out. She sticks a large needle into him to extract a liver sample and admits to the charge, rationalizing that they are even because he drugged her and made her think that she was dying. When she leaves the room, House swipes her water bottle, to test for Huntington's.
Wilson reproaches House for risking his life, yet again, by having the transfusion of potentially lethal blood. In their discussion of bad blood, House realizes that it wasn't a bad batch of blood that caused Flynn's symptoms, but the wrong blood type. He asks Flynn what his blood type is, and Flynn says A, but the blood they both received was AB. An autoimmune disease caused Flynn's blood to appear to be AB. For the first time, the correct diagnosis was actually lupus.
Cole nominates Amber and Kutner to be fired. Kutner is a surprising choice because Cole and he are friends. House questions this decision but Cole offers no explanation. House deduces that the reason he nominated Kutner is because Kutner is a liability to the hospital, and Cuddy and Cole struck a deal. Since the object of the challenge was not to get caught, this collusion was against House's rules. House does not want anyone to give Cuddy power over House's team, so he fires Cole. Not only did this deal cost Cole his job, it also cost him his friendship with Kutner. While the other doctors say goodbye to Cole, Kutner walks away.
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