When we last left House, he had just lost a patient after amputating her leg at a horrific disaster scene. In the depths of despair (even Foreman is concerned), House returns home and to the possibility of returning to Vicodin. “He is bereft,” said Hugh Laurie in interview footage provided by Fox. "He’s formed an emotional connection with her,” and her death hits him hard. But also, says Laurie, it's because his powerful intellect has failed him and “his intellect is all he has.”
But as he sits in his darkest hour sitting on his bathroom floor, an angel in pink appears at his bathroom door at this critical juncture. It is (as Laurie puts it) “the saintly Cuddy” to pronounce to the stunned House that she has ended her brief engagement to Lucas Douglas. She cannot get House out of her head— no matter how happy she is supposed to be with a “new fiancé and a new house.” Season six ends on the clasped hands of a finally-united House and Cuddy after she declares to him, “I love you,” despite all her efforts to stay emotionally detached from him.
Season seven begins moments later with House and Cuddy standing in his bedroom with Cuddy tending to his physical (he was badly banged up in the season six finale) as well as his emotional wounds. It’s a powerful scene—something I won’t spoil. I’ll just say that my eyes misted and it’s a very important moment for both characters—and especially for House—to experience on several levels.
It’s no secret that it all leads to lovemaking and House’s inevitable “now what?” Cuddy wants to go home, shower and go to work; House wants to capture this moment and let it linger into the rest of the day, calling himself in—and convincing Cuddy to play hooky as well.