RJ's Pick: Carolina by 3
Seattle (2-1) at San Francisco (2-1) *Monster Park* - 4:05 PM (Sheridan's line: Seattle by 2)
San Francisco isn't as good as their 2-1 record would seem to indicate. Their two wins came from barely beating the Cardinals and barely beating the Rams. Last week, they were shredded by Pittsburgh. The 49ers could easily be 0-3 right now. Meanwhile, the Seahawks would be 3-0, except for a late-fourth quarter collapse in Arizona back in Week Two. This game should be kept close, however, because it's at Monster Park.
RJ's Pick: Seattle by 4
Kansas City (1-2) at San Diego (1-2) *Qualcomm Stadium* - 4:15 PM (Sheridan's line: San Diego by 12)
San Diego has been unimpressive so far this year, as has their star RB LaDainian Tomlinson. He is averaging just 2.3 yards per carry, and has as many passing TDs this season as rushing TDs (1). However, the Chargers should improve as the season wears on. Kansas City, meanwhile, is just thoroughly bad. Their defense isn't horrible, but their offense certainly is. San Diego is going to win this game, but I'm not sure if it will be a low-scoring game with a small margin of victory, or a total blowout. That's the only tough part about making this pick.
RJ's Pick: San Diego by 17
Pittsburgh (3-0) at Arizona (1-2) *University of Phoenix Stadium* - 4:15 PM (Sheridan's line: Pittsburgh by 6)
This game should be a rout, since the Steelers are playing as good as anybody right now (with the possible exception of the Patriots). But Kurt Warner is in at QB for the Cardinals, and he looked very impressive last week taking over for Matt Leinart. I don't expect an upset, but Warner could keep it close.
RJ's Pick: Steelers by 3
Denver (2-1) at Indianapolis (3-0) *RCA Dome* - 4:15 PM (Sheridan's line: Indianapolis by 9½)
Denver nearly lost to the hapless Bills in Week One, then nearly lost to the Raiders in Week Two. Last week, they got whipped at home by the Jaguars, and their running game was completely shut down. Indianapolis looked beatable the last two weeks, but both were away games. They aren't going to lose at home this week (or perhaps all season).