From there you just put the transmitter on your camera and the transceiver on to the flash and for basic mode shooting you are ready to go. You can shoot just like you would if you had the flash on your camera. You can shoot in E-TTL mode or manual or a combination of both. I was even able to shoot at speeds from 250-8000 with nice even light.
You can also use the FlexTT5 to trigger a Canon Speedlight in manual mode or to trigger a manual flash (studio pack, moonlight, non-Speedlight hotshoe flash) when used with the P2 port. Other brands of flash may or may not work in manual mode as well. There are other PocketWizard transceivers that will work with non-Speedlight flashes and these can be triggered with the MiniTT1. In fact you may have as many remote transceivers on the same channel as you want giving you unlimited possibilities.
Once I got everything setup with the FlexTT5, I found the set to be incredibly reliable and easy to use. I do not think I have had a misfire yet. I have used them to shoot with flashes in E-TTL and manual as well as using Alien Bees studio lights.
I really like the smallness of MiniTT1 - you really almost forget that it is on your camera. I also like flatness of the FlexTT5's design as well. With all of the configuration abilities and reliability, if you want professional grade remote flash triggering, then I can highly recommend the MiniTT1 and FlexTT5.