If you are new to GUI development and want to avoid some of the extra information in Part 1, I would recommend you read all of Chapter 1, then skim Chapters 2 and 3 for the basic concepts that are presented, then skip Chapters 4 and 5, and head directly to Chapter 6. Engineers with previous GUI development experience can probably skip Chapters 2-5, then read Chapter 6.
Please don't let these few criticisms deter you from buying this book. Overall, wxPython in Action does a great job of pulling together a tremendous amount of material. And for the most part, the writing is easy to read, concise, and cogent. I think this a great first effort for both authors, and an extremely useful resource for the Python community.
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