Every phrase of that Kessler quote brims with foolishness. "Arab anger at a perceived bias against the Palestinians" is Condoleezza Rice's fault? How about that it's the fault of Palestinian's for being monstrous barbarians. The Bush administration hasn't made enough of an effort to take their side of things? But they mostly don't have a legitimate side to take. Is it Kessler's contention that if Condi coddled the Palestinians better, there'd be less killing?
By his lights, the Israel-Hezbollah war in Lebanon in 2006 somehow represents a foreign policy failure by Rice. Also, the lack of progress in the supposed Israeli-Palestinian "peace process" apparently counts as her failure. How figure that as the fault of any American? Hey, I'm no fan of Bill Clinton or Madeleine Albright, but Arab barbarity isn't their fault either.
What "missed opportunity with Iran" might there have been? Other than destroying them militarily, what exactly is it that we could do to dissuade those evil bastards from their brutal rogue ways? Did Clinton or Bush the elder or even the great Ronald Reagan have them under control? I think not. Oh wait - I know what we need: more diplomacy and dialogue with the Iranian regime.
Now, it's perfectly reasonable to hold the Bush administration responsible for missteps in the conduct of the Iraq invasion - though that would be more on Secretary of Defense Rumsfeld or Decider in Chief Bush, rather than Ms Rice at State. If we'd done this and that differently, maybe we'd have gotten different and better results.
But it's nonsense to blame any American for the hatefulness and barbarity of thousand year old conflicts on the other side of the world.