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International Society for Stem Cell Research Assesses New Treatments

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The International Society for Stem Cell Research (ISSCR) has provided guidance on the selection of stem cell protocols for patients and their medical providers. The Society has stated, for one thing, that stem cells for bone marrow aren’t interchangeable with stem cells for the brain. In addition, a single type of stem cell treatment cannot be used for multiple applications.

Image credit: Wikipedia Commons

Image credit: Wikipedia Commons

Blood stem cell transplantation is the most widely used for treating diseases of the blood and the autoimmune system. Bone marrow applications have been successful because the task at hand is to make more blood. In February 2010 the British company ReNeuron announced it had been approved to conduct a Phase I clinical trial of a neural stem cell treatment for stroke. The first embryonic stem cell-based treatment for acute spinal cord injury has been authorized by the U.S. Food and Drug Administration (FDA) to move into Phase I clinical trials, according to the ISSCR.

The ISSCR is considering a recent task force recommendation that it review clinics for inclusion on its website. Upon receipt of a request, the ISSCR would ask the named clinic to provide the evidence that the treatment it offers has appropriate oversight and other standard patient protections. The ISSCR will publish online whether or not the clinics have provided that information. Implementation of this recommendation would provide patients and their medical providers with authoritative support for making decisions regarding treatment by specific clinics throughout the world.

The National Institutes of Health (NIH) has set forth guidelines for human stem cell research. In summary, the guidelines consist of an exhaustive definition of what exactly human embryonic stem cells (hESCs) are. The NIH has defined human embroyonic stem cells to be “cells that are derived from the inner cell mass of blastocyst stage human embryos, are capable of dividing without differentiating for a prolonged period in culture, and are known to develop into cells and tissues of the three primary germ layers. Although hESCs are derived from embryos, such stem cells are not themselves human embryos.”

The NIH Stem Cell Unit (SCU) has acquired 21 previously approved and available hESC lines listed from BresaGen, Inc.; ES Cell International; Technion-Israel Institute of Technology; the University of California, San Francisco; the Wisconsin Alumni Research Foundation (WiCell Research Institute); and Cellartis AB. Stem cell research and implantation is an evolving field. Patients and their medical providers should consult with the ISSCR and the NIH SCU on specific stem cell applications, their efficacy, and the approved clinics for performing any transplantation being considered.

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About Dr Joseph S Maresca

I've taught approx. 34 sections of collegiate courses including computer applications, college algebra, collegiate statistics, law, accounting, finance and economics. The experience includes service as a Board Director on the CPA Journal and Editor of the CPA Candidates Inc. Newsletter. In college, I worked as a statistics lab assistant. Manhattan College awarded a BS in an allied area of operations research. The program included courses in calculus, ordinary differential equations, probability, statistical inference, linear algebra , the more advanced operations research, price analysis and econometrics. Membership in the Delta Mu Delta National Honor Society was granted together with the degree. My experience includes both private account and industry. In addition, I've worked extensively in the Examinations Division of the AICPA from time to time. Recently, I passed the Engineering in Training Exam which consisted of 9 hours of examination in chemistry, physics, calculus, differential equations, linear algebra, probability/ statistics, fluids, electronics, materials science/structure of matter, mechanics, statics, thermodynamics, computer science, dynamics and a host of minor subject areas like engineering economics. A very small percentage of engineers actually take and pass the EIT exam. The number has hovered at circa 5%. Several decades ago, I passed the CPA examination and obtained another license in Computer Information Systems Auditing. A CISA must have knowledge in the areas of data center review, systems applications, the operating system of the computer, disaster recovery, contingency planning, developmental systems, the standards which govern facility reviews and a host of other areas. An MBA in Accounting with an Advanced Professional Certificate in Computer Applications/ Information Systems , an Advanced Professional Certificate in Finance and an Advanced Professional Certificate in Organizational Design were earned at New York University-Graduate School of Business (Stern ). In December of 2005, an earned PhD in Accounting was granted by the Ross College. The program entrance requires a previous Masters Degree for admittance together with a host of other criteria. The REGISTRAR of Ross College contact is: Tel . US 202-318-4454 FAX [records for Dr. Joseph S. Maresca Box 646 Bronxville NY 10708-3602] The clinical experience included the teaching of approximately 34 sections of college accounting, economics, statistics, college algebra, law, thesis project coursework and the professional grading of approx. 50,000 CPA examination essays with the American Institute of Certified Public Accountants. Additionally, membership is held in the Sigma Beta Delta International Honor Society chartered in 1994. Significant writings include over 10 copyrights in the name of the author (Joseph S. Maresca) and a patent in the earthquake sciences.