Then there's the clock issue. Each mission has a set time at which it can first be accomplished and a set time by which you have to start it, and there are a lot of things to do in your 72 hours. While that gives you some choices, it also means that you're going to regularly feel like you've made the wrong choice or haven't allocated your time properly. It is here where the game feels like it wants to be a dramatic one despite all the humorous shenanigans. Missing a mission very well may mean that people are dying in Fortune City, people you could have saved. That should carry some weight to it, and it almost feels like Dead Rising 2 wants it to, but it the game doesn't seem to know how to make that happen, it's just another mission you didn't complete which means that you'll not get a 100% completion and may want to go back through the game again… if you don't mind redoing all the required tasks and aren't bored by the respawned undead and weapons.
Where the game fails again is with its cutscenes. Ignoring the not terribly sharp graphics and bad lip-synch, Dead Rising 2 does a poor job of translating in game choices to the cutscenes, and the fact that it tries just makes the mistakes more glaring. For instance, as with the first Dead Rising, you can go around trying on different outfits in stores and what you're wearing will be reflected correctly in a cutscene. However, let's say that you opted to try to rescue an old lady and on your way back tot the safe house you had to do a story critical mission. Naturally, you've thrown the old lady over your shoulder so that she shouldn't fall behind and get her brains sucked on. She won't be there in the cutscene for the mission you've opted to start while doing the sidequest, she'll be back on your shoulder once the scene ends, but she won't be in the scene.
Do not fear though, young adventurer, the game doesn't just fail, you will too… repeatedly. Seriously, you're going to die, you're going to lose missions, and you're going to have to go back to a previous save point or start the story over (a nice convenient option every time you fail in a critical area). There are some advantages to your inadequacies however, namely that while your kill count will drop back to where it was the last time you saved, your experience points and level you've achieved won't. That means that any new combos you've learned, strength you've gained, larger inventory, etc., will be available to you once you've taken your two steps back. That does make it a lot easier on subsequent playthroughs (which, again, there will be).