Further versatility comes from altering the deck. For beginner players, take Special Cards out of play or lessen the number of score cards needed for victory. For more advanced players, decrease the score cards. For fewer players, take out a few Special Cards. The official rules include a Solitaire Play with no special cards and running through ten Matrices trying to solve each, which proves to be challenging in itself.
The most chance for versatility, however, comes from home rules. Maybe players have to complete exactly the number of lines on their score cards with too many counting against them. Or perhaps Drop cards might be split. Or edit a Power Up or two to increase the number of cards in hand. Or players might play multiple cards at a time. This is a great game for those who like to tweak the possibilities.
While some might think of Tetris as a boring way to play with blocks, it is definitely a good game to master spatial thinking, and Tetris the Card Game allows a new level for creativity.