But then attention spans might fall too, because too much freedom can also be too much distraction. The internet has already conditioned users to read shorter blocks of text. Other effects would include complicated copyright issues. Piracy might take over the literary world in ways unimaginable before (but then some people will always argue that piracy is actually good for authors because it allows greater exposure to their readers).
Nevertheless in the future, the newer e-book readers will seem so normal and natural, that people would wonder about the backwardness of the times when trees were cut to create those cumbersome un-interactive visual mediums of information transcription. And people will shake their heads in pity at their technology-challenged ancestors. This is how it has always been - the future always pitying the past.
But of course this will too soon be replaced by newer technologies. My best bet is electrodes in the head that download information directly to the brains. Two hundred years from now is my uneducated, vague and random guess. And then we shall talk about the anticipated extinction of e-book readers.