Look at it this way. Before adjusting for home field advantage (which doesn't seem to matter much to the Peytons and the Bradys) the DVOA differential between the Colts and the Panthers is much greater than the differential between the Pats and the 'Skins. But the Colts are only giving 6.5 while the Pats are giving 17. Gotta buy Indy and sell New England in that circumstance.

Money Line
Here's the money line spreadsheet.

Since the money line depends on teams winning or losing outright, the goals of the gambler and the goals of the players are in perfect sync, so we let the formula do the picking for us — no judgments or mitigations allowed. And the formula gives us (the dollar amount is the payouts for a $100 bet):

Detroit $210
Cleveland $63.29
Jacksonville $183
Buffalo $130
New Orleans $70.92
Green Bay $161

Notice from the spreadsheet that the formula selects the Eagles before the home adjustment and the Vikings after. In cases such as this we have leeway, but I'll pass on taking either of these teams — unless the Eagles are going to wear those cartoon uniforms like they did against the Lions. In that case I'll take the Eagles.

Also note that the payoff for a $100 bet on the Redskins to win is $1200 dollars and the formula still won't let me take the 'Skins. A 12/1 win can make your whole season. If I was to gamble in real life, which I never do as far as you know, there's no way I could resist that.

Recap

Point Spread:
Bills +3
Packers +4
Steelers -4
Browns -3
Colts -6.5
Redskins +17

Money Line:
Detroit $210
Cleveland $63.29
Jacksonville $183
Buffalo $130
New Orleans $70.92
Green Bay $161

I had to push this column out a bit early this week so there was no line set on the Chargers/Texans game. Sorry to rush it, but I have to leave town for a few days. There are some angry Australians threatening to slather me with Vegemite and feed me to the dingos.