We share 60% of our DNA with... chickens
Published December 09, 2004
He said the completion of the sequencing effort, which had cost $13m, was most welcome.
"The basic scaffold is there. Now we have to attach the meaning to it - it needs people to annotate the sequence, to say where the genes are," he said.
"The project will bring together all the biological knowledge about the chicken."
Scientists will compare the data with the human code to see if there is information there that can throw light on our own biochemical make-up.
Recent outbreaks of avian flu have accelerated researchers' interest in learning more about the chicken genome and how genetic variation may play a role in the susceptibility of different strains to the disease.
In addition to its tremendous economic value as a source of eggs and meat, the chicken (Gallus gallus) is widely used in biomedical research.
It serves as an important model for the study of embryology and development, as well as for research into the connection between viruses and some types of cancer.
The Washington University researchers, directed by Dr. Richard Wilson, deposited the initial assembly into the GenBank database for worldwide release.
The draft has been used by a team, led by the Beijing Genomics Institute in China and supported by the Wellcome Trust in Britain, to create a map of genetic variation for three different strains of domestic chickens.
The strains were a broiler strain from the United Kingdom, a layer strain from Sweden and a Silkie strain from China.
To make the map, researchers identified and analysed about two million genetic variation sites, mostly single nucleotide polymorphisms (SNPs).
SNPs are minute variations scattered through the DNA sequence and make a major contribution to the differences between individual animals in a species.
"We can use this knowledge of genetic variation to map characteristics that could be production traits, such as how fast they grow," said Dr Burt.
Cluck, cluck.
- We share 60% of our DNA with... chickens
- Published: December 09, 2004
- Type:
- Section: Culture
- Writer: bookofjoe
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Always you with the compelling articles . . .
(not stalking you still)
ML
Pied Psittacine Piper
Parrotty Poobah
and Keeper of the Coup
(think: Cuba)