Bob Roberts (Bob Roberts)
Whoa boy, his lust for power entailed such direct wickedness as faking an assassination attempt, and then murdering a reporter who was on to his long history of drug running and ripping off S&Ls. Plus, he's a Republican. What more need be said?

Dr Yen Lo (The Manchurian Candidate)
Evil often has a charming face. That seductive quality contributes greatly to making it really nasty. Good humor invites you to join in the evil. "I've allowed my people to have a little fun in the selection of bizarre tobacco substitutes... Yak dung! ...Oh, tastes good — like a cigarette should!"

Mr. Scratch (The Devil and Daniel Webster)
How much more evil can you get than the frickin' devil himself- and a far more subtle and nuanced Prince of Darkness than, for example, Al Pacino.

Rev. Harry Powell (Night of the Hunter)
This guy is the boogeyman of my nightmares, not some horribly contrived Freddy Kreuger.

Lady Mary Van Tassel (Sleepy Hollow)
Sold her soul to the devil for revenge. She had different brilliantly evil ways to compromise every person around.

Matthew Harrison Brady (Inherit the Wind)
This doppleganger for William Jennings Bryan may not have been a murderer, but it's only by accident of place and time, for he represents the face of pure demagoguery. He says stupid crap that he knows better than to bump the boobs into line, with no regard for truth or consequences. Like a good demagogue, you can see him talking himself into half-believing his own crap.

Baby Jane Hudson (Whatever Happened to Baby Jane?)
Killing her sister's pet bird, then putting it on plate to serve for lunch - wow!

Norma Desmond (Sunset Boulevard)
Her real crime was not so much against the murdered screenwriter as against the butler/ex-husband whom she has heedlessly kept around in such wicked torment for so many years.

Franz Becker (M)
Oh, he can't help it. He's got a compulsion that MAKES him a monster, something inside that he can't control. Shut up.

Doyle Hargraves (Sling Blade)
Mundane everyday evil incarnate, Doyle couldn't really help it. See, he had a bad childhood, or something. Therefore, he couldn't really help smacking the woman and child around a little, and being abusive to anyone stupid enough to associate with him. This is just the kind of pussy-man behavior that makes me nuts. Boo hoo ya frigging baby.

Judd Frye (Oklahoma!)
Steiger's performance in the smokehouse during "Poor Judd Is Dead" must rate as one of the top displays of self-pity ever. Pure class resentment permeated every fiber of his being, and motivated every hateful display- which is to say almost his every action or word in the entire movie.